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Study identifier: NCT06450678 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Use of a Physiotherapy Assessment to Predict Extubation Failure in Mechanically Ventilated Patients: the EPIC Assessment

Condition: Mechanical Ventilator Weaning · Mechanical Ventilation  ·  Sponsor: Assistance Publique - Hôpitaux de Paris

PhaseN/A
Planned participants330
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

"Weaning from mechanical ventilation is a crucial step in the intensive care unit. Several factors complicate weaning and increase the risk of failure. To predict the success of extubation, the spontaneous ventilation test (T-Tube) remains essential. Despite this, the failure rate is around 10-20%. Failed extubation is not without consequences, since it increases the risk of pneumopathy and mortality. It therefore seems essential to identify potential extubation failures using effective predictive criteria. Several of these predictive criteria have been studied separately in the literature, but are still not widely used in practice. Many studies have sought to identify these predictive criteria, without actually linking them. However, when combined in a single assessment prior to extubation, they could represent a reliable prediction and decision-making aid. In the intensive care unit at Hôpital Bichat Claude Bernard, a team of physiotherapists dedicated solely to this unit carries out a routine EPIC Assessment, combining several criteria, some of which have individually demonstrated their reliability in predicting extubation outcome. Physiotherapists are health professionals working as part of the intensive care team, and are well versed in issues relating to bronchial congestion, respiratory function and muscle strength, whether for breathing or locomotion. Similarly, their involvement in issues relating to swallowing disorders acquired in intensive care gives them an ove…

This description comes directly from the study's public registry record.

Talk to the study team

Antoine SHENOUDA, Physiotherapist  ·  06 52 94 89 74  ·  antoine.shenouda@aphp.fr

Michael THY  ·  michael.thy@aphp.fr

Always discuss trial participation with your own doctor first.

Locations (1)

Bichat - Claude Bernard HospitalParis, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT06450678