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Study identifier: NCT06449677 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Bionic Pancreas in CFRD

Condition: Cystic Fibrosis-related Diabetes  ·  Sponsor: Jaeb Center for Health Research

PhasePhase 3
Planned participants150
Who can joinAll sexes, 14 Years to no upper limit
Healthy volunteersNo

About this study

This multi-center randomized controlled trial (RCT) will compare efficacy and safety endpoints using the insulin-only configuration of the iLet Bionic Pancreas System (BP) versus a control group using their usual care insulin delivery method and continuous glucose monitoring (CGM) during a 13-week study period in individuals ≥14 years old with cystic fibrosis-related diabetes (CFRD). After 13 weeks, participants will continue in a 13-week Extension Phase in which the BP group will continue to use the BP system and the Usual Care group will initiate use of the BP system.

This description comes directly from the study's public registry record.

Talk to the study team

Judy Sibayan, MPH  ·  813-975-8690  ·  jsibayan@jaeb.org

Always discuss trial participation with your own doctor first.

Locations (16)

University of Colorado-Barbara Davis Center for DiabetesAurora, Colorado, United StatesRecruiting
Yale University School of MedicineNew Haven, Connecticut, United StatesRecruiting
Emory UniversityAtlanta, Georgia, United StatesRecruiting
Indiana University School of MedicineIndianapolis, Indiana, United StatesRecruiting
Johns Hopkins University School of MedicineBaltimore, Maryland, United StatesRecruiting
Massachusetts General HospitalBoston, Massachusetts, United StatesRecruiting
University of MinnesotaMinneapolis, Minnesota, United StatesRecruiting
Children's Mercy HospitalKansas City, Missouri, United StatesRecruiting
Columbia University Medical CenterNew York, New York, United StatesRecruiting
University Hospitals of ClevelandCleveland, Ohio, United StatesRecruiting
Children's Hospital of PhiladelphiaPhiladelphia, Pennsylvania, United StatesCompleted
UT Southwestern Medical CenterDallas, Texas, United StatesRecruiting

+ 4 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06449677