Condition: Drug Induced Liver Injury · Pruritus · Sponsor: University of Nottingham
Idiosyncratic drug-induced liver injury (DILI) is an unpredictable adverse hepatic reaction to a medication used in its therapeutic dose. DILI is the second most common cause of itching in adult Hepatology after biliary obstruction. In particular cholestatic or mixed pattern types of DILI (in which bile flow from the liver is impaired) are associated with long-lasting effects as well as reduced quality of life. There is therefore an urgent need to determine the incidence and natural history of itching in DILI and establish a network of centres that will form a basis for a clinical trial to investigate a novel intervention to treat these.
This description comes directly from the study's public registry record.
Elinor Study Coordinator · 0115 7484390 · Elinor.Cross@nottingham.ac.uk
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| Nottingham University Hospitals NHS Trust | Nottingham, United Kingdom | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06446609