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Study identifier: NCT06446453 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Echography-guided Surfactant THERapy (ESTHER) For Preterm Infants With Respiratory Failure

Condition: Respiratory Distress Syndrome, Newborn · Pulmonary Surfactants · Intensive Care Units, Neonatal  ·  Sponsor: Connecticut Children's Medical Center

PhaseNA
Planned participants52
Who can joinAll sexes, 0 Hours to 2 Hours
Healthy volunteersNo

About this study

Point-of-care ultrasound (POCUS) is the use of ultrasound by the bedside provider in real time to answer a specific question and guide medical management. POCUS can be used to diagnose the severity of neonatal respiratory distress syndrome (RDS) through a lung ultrasound score. Lung ultrasound scores have also been shown to predict if an infant is treated with an initial dose of surfactant. Therefore, using lung ultrasound scores to guide surfactant therapy for RDS will likely lead to earlier surfactant therapy and may improve short-term respiratory outcomes. This study will test this theory by comparing lung ultrasound score-guided surfactant therapy for premature infants with RDS with our current surfactant administration guidelines.

This description comes directly from the study's public registry record.

Talk to the study team

Jacob Kelner  ·  860-545-9720  ·  jkelner@connecticutchildrens.org

Always discuss trial participation with your own doctor first.

Locations (1)

Connecticut Children'sHartford, Connecticut, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06446453