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Study identifier: NCT06445738 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Post-operative Radiotherapy Omission in Selected Patients With Early Breast Cancer Trial International VErsion (PROSPECTIVE)

Condition: Breast Cancer · Breast Cancer Female  ·  Sponsor: Breast Cancer Trials, Australia and New Zealand

PhaseNA
Planned participants1400
Who can joinFemale, 50 Years to no upper limit
Healthy volunteersNo

About this study

The PROSPECTIVE trial aims to find out if using the results of Magnetic Resonance Imaging (MRI) for early breast cancer can select people to not have radiotherapy and still have a low chance of the cancer coming back after surgery. The main question it aims to answer is: \* Will cancer come back in the same breast as the original cancer in patients who have surgery for their breast cancer, but who don't have radiotherapy afterwards because the results of an MRI before surgery showed favourable characteristics for not having radiotherapy.

This description comes directly from the study's public registry record.

Talk to the study team

Heath Badger  ·  +61 2 4925 5239  ·  heath.badger@bctrials.org.au

Always discuss trial participation with your own doctor first.

Locations (9)

UCSF Breast Care CenterSan Francisco, California, United StatesNot Yet Recruiting
Baylor St Luke's Medical CentreHouston, Texas, United StatesNot Yet Recruiting
The Chris O'Brien LifehouseCamperdown, New South Wales, AustraliaNot Yet Recruiting
Lake Macquarie Private HospitalGateshead, New South Wales, AustraliaNot Yet Recruiting
Mater Hospital, SydneyNorth Sydney, New South Wales, AustraliaRecruiting
Westmead HospitalWestmead, New South Wales, AustraliaNot Yet Recruiting
Royal Adelaide HospitalAdelaide, South Australia, AustraliaNot Yet Recruiting
Monash Cancer Centre (MMC Moorabbin)Clayton, Victoria, AustraliaRecruiting
The Royal Melbourne HospitalMelbourne, Victoria, AustraliaRecruiting

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Source record: clinicaltrials.gov/study/NCT06445738