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Study identifier: NCT06444841 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Paper-Based and Smartphone-Based Memory Supports

Condition: Alzheimer Disease · Dementia, Mild · Mild Cognitive Impairment  ·  Sponsor: Baylor University

PhaseNA
Planned participants200
Who can joinAll sexes, 50 Years to no upper limit
Healthy volunteersNo

About this study

Alzheimer's disease and related dementias lead to marked declines in daily functioning, independence, and quality of life. One of the earliest cognitive changes in these conditions is impairment in prospective memory, or the ability to remember future intentions such as taking medications at a given time. Prior intervention studies that targeted prospective memory used mnemonic strategies or cognitive training, but these approaches resulted in modest gains in clinical populations. By contrast, a Stage I pilot trial indicated that smartphone-based memory aids (reminder apps) can be accepted and used by persons with mild cognitive impairment and mild dementia to improve both subjective and objective prospective memory performance. The investigators will now test for efficacy, durability, and generalizability of benefits across diverse samples in a Stage II randomized controlled trial. Some 200 participants with mild cognitive impairment or mild dementia will be recruited, half of whom will be from digitally-disadvantaged backgrounds (low socioeconomic status, rural, or historically underrepresented groups). Participants will complete baseline assessments and then be randomly assigned to a smartphone reminder app intervention or an active control condition that uses a paper- based memory support system. Across a 4-week intervention period, participants will complete patient-selected and experimenter-assigned prospective memory assessments and receive booster training sessions to…

This description comes directly from the study's public registry record.

Talk to the study team

Michael Scullin, PhD  ·  254-710-2251  ·  michael_scullin@baylor.edu

Jared Benge, PhD  ·  512-495-5285  ·  jared.benge@austin.utexas.edu

Always discuss trial participation with your own doctor first.

Locations (3)

UT Health Austin Comprehensive Memory CenterAustin, Texas, United StatesRecruiting
Baylor Scott & White HealthcareTemple, Texas, United StatesNot Yet Recruiting
Baylor UniversityWaco, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06444841