Condition: Spinal Cord Injuries · Pain, Neuropathic · Nociceptive Pain · Sponsor: University of Zurich
The development of neuropathic pain is one of the most debilitating sequels after a spinal cord injury (SCI). The overall aim of this study is to investigate potential underlying pathophysiological mechanisms of neuropathic pain after SCI. The functionality of the nociceptive pathway in humans as well as its plastic changes following SCI will be inferred with sophisticated sensory and pain phenotyping using quantitative sensory testing (i.e., psychophysical measures), objective neurophysiological measures of pain processing and the recording of pain-related autonomic responses (i.e., galvanic skin response, cardiovascular measures and pupil dilation). In addition, the interplay between the somatosensory and autonomic nervous system and its association with the development and maintenance of neuropathic pain after SCI will be investigated.
This description comes directly from the study's public registry record.
Michèle Hubli, PD Dr. · +41 44 510 72 03 · michele.hubli@balgrist.ch
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| Balgrist University Hospital | Zurich, Canton of Zurich, Switzerland | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06443281