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Study identifier: NCT06442995 Synced from ClinicalTrials.gov · July 28, 2026
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Evaluation of the Efficacy of the Addition of Magnesium Sulfate to Morphine on the Occurrence of Acute Urinary Retention Following Epidural Anesthesia for Cesarean Section.

Condition: Urinary Retention  ·  Sponsor: CHU de Reims

PhasePhase 4
Planned participants290
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

Peri-medullary anesthesia is the preferred anesthetic technique for Caesarean surgery. Compared with general anesthesia, it reduces maternal and fetal morbidity and mortality, as well as postoperative pain. However, this technique exposes the patient to the adverse effects of peri-medullary morphine, particularly the risk of postoperative urinary retention. Urinary retention during the first 72 hours after Caesarean section affects around 33% of parturients. This is a particularly debilitating event for parturients, exposing them to the risk of further urinary catheterization, increased theoretical risk of urinary tract infection, traumatic urethral injury, hindered accelerated rehabilitation and altered maternal satisfaction. Several studies have demonstrated the benefits of adding magnesium sulfate to epidural anesthesia for Caesarean sections, notably by reducing postoperative pain. Magnesium sulfate may also have a facilitating effect on postoperative micturition, thanks to its sympathicolytic effect. This hypothesis is supported by a retrospective study carried out in our maternity hospital, which showed a 15% reduction in post-Caesarean urinary retention when women were given magnesium sulfate in addition to the drugs traditionally used for epidurals. This little-known property needs to be clarified

This description comes directly from the study's public registry record.

Talk to the study team

Maxime Riffault  ·  00336 79 63 29 55  ·  mriffault@chu-reims.fr

Always discuss trial participation with your own doctor first.

Locations (1)

Chu ReimsReims, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT06442995