Condition: Hepatic Impairment (HI) · Sponsor: Merck Sharp & Dohme LLC
The purpose of this study is to compare the plasma pharmacokinetics (PK) of nemtabrutinib (MK-1026) following a single oral dose of nemtabrutinib in participants with moderate hepatic impairment to that of healthy matched control participants and to evaluate the safety and tolerability of nemtabrutinib.
This description comes directly from the study's public registry record.
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| Clinical Pharmacology of Miami ( Site 0003) | Miami, Florida, United States | Active Not Recruiting |
| Orlando Clinical Research Center ( Site 0001) | Orlando, Florida, United States | Active Not Recruiting |
| Texas Liver Institute ( Site 0002) | San Antonio, Texas, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06442436