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Study identifier: NCT06440408 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Calculating Wall Shear Stress in Infant Pulmonary Veins

Condition: Pulmonary Vein Stenosis  ·  Sponsor: Children's Hospital of Philadelphia

PhasePhase 1
Planned participants20
Who can joinAll sexes, N/A to 18 Years
Healthy volunteersNo

About this study

The purpose of this study is to better understand pediatric pulmonary vein stenosis (PVS), which is the narrowing of blood vessels that connect the lungs to the heart. PVS is a life-threatening disease without a clear cause. The investigators think patients who develop PVS have an increased Wall Shear Stress (WSS) level in the pulmonary veins, which is the force placed on the walls of the veins. This study will determine if WSS can be calculated in the pulmonary veins of infants using Ferumoxytol enhanced Cardiac Magnetic Resonance Imaging (FcMRI). If possible, the investigators aim to use FcMRI to better screen patients at risk of PVS and to help guide therapy in patients with PVS.

This description comes directly from the study's public registry record.

Talk to the study team

Ryan Callahan, MD  ·  267-426-2957  ·  callahanr2@chop.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Children's Hospital of PhiladelphiaPhiladelphia, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06440408