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Study identifier: NCT06440057 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Dose Escalation Study of ZG006 in Participants With Advanced Small Cell Lung Cancer or Neuroendocrine Carcinoma, Followed by Dose Expansion Study in Participants With Neuroendocrine Carcinoma.

Condition: Neuroendocrine Carcinoma  ·  Sponsor: Suzhou Zelgen Biopharmaceuticals Co.,Ltd

PhasePhase 1/Phase 2
Planned participants78
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This is a multicenter, open-label phase I/II study, divided into 2 parts: Part 1 involves a dose-escalation study of ZG006 in which the safety and tolerability of ZG006 in patients with advanced small cell lung cancer or neuroendocrine carcinoma are explored. Upon completion of Part 1, investigators and the sponsor will discuss and determine two recommended phase II doses (RP2D) based on safety, preliminary efficacy, and pharmacokinetic results for use in Part 2. Part 2 is a phase II dose-expansion study of ZG006, aiming to investigate the efficacy and safety of ZG006 in patients with Neuroendocrine Carcinoma.

This description comes directly from the study's public registry record.

Talk to the study team

Shangdi Ning  ·  +86-0512-57309965  ·  ningsd@zelgen.com

Always discuss trial participation with your own doctor first.

Locations (1)

Chinese PLA General HospitalBeijing, Beijing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06440057