Condition: Acute Hypoxemic Respiratory Failure · Mechanical Ventilation · Sponsor: Erasmus Medical Center
The goal of this physiological intervention study is to unravel the (patho)physiological mechanisms and potential clinical benefits of a pre-specified early switch from controlled to assisted ventilation in mechanically ventilated adult patients with acute hypoxemic respiratory failure (PaO2/FiO2 ratio \< 200 mmHg). The intervention is that participants will be switched from controlled to assisted ventilation when PaO2/FiO2 ratio \> 200 mmHg. The primary endpoint is the change in regional lung stress (as derived by electrical impedance tomography) when switching from controlled to assisted ventilation and until a successful or failed switch.
This description comes directly from the study's public registry record.
Annemijn Jonkman, PhD · +3110-7035142 · a.jonkman@erasmusmc.nl
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| Erasmus MC | Rotterdam, Netherlands | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06438198