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Study identifier: NCT06434207 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Extracellular Vesicle Micro RNA Profiling in Congenital Heart Disease: Fetal-Maternal Regulation in Neonatal Thrombosis

Condition: Congenital Heart Disease · Single-ventricle · Thrombosis  ·  Sponsor: Boston Children's Hospital

PhaseN/A
Planned participants10
Who can joinAll sexes, 1 Day to 7 Days
Healthy volunteersNo

About this study

Newborns with congenital heart disease (CHD) are at increased risk of developing postpartum and postoperative blood clots after cardiac surgery. The molecular mechanisms that are responsible for the clotting profile predisposing children to blood clots in the early stages of life are currently not well described. The goal of this proposal is to prospectively collect plasma samples from ten (10) neonates with antenatal diagnosis of severe congenital heart disease (CHD) to better understand mechanisms responsible for abnormal clotting in the perioperative period.

This description comes directly from the study's public registry record.

Talk to the study team

Rachel Bernier, MPH  ·  857-218-5348  ·  rachel.bernier@childrens.harvard.edu

Hanna Van Pelt, BS  ·  hanna.vanpelt@childrens.harvard.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Boston Children's HospitalBoston, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06434207