← Eichor
Study identifier: NCT06430736 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

PRONTO Trial (PRophylactic Versus ON-demand Use of TOcilizumab)

Condition: Myeloma · Lymphoma · Leukemia  ·  Sponsor: Insel Gruppe AG, University Hospital Bern

PhasePhase 2
Planned participants100
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Despite the consequent use of Tocilizumab together with conventional antipyretics at early/first signs of emerging CRS, CRS (and eventually the subsequent development of ICANS) remain a major concern for patients. This study aims to identify safety and efficacy of prophylactic Tocilizumab treatment. In particular, to explore whether prophylactic Tocilizumab treatment can decrease the incidence and severity of CRS (and subsequent eventual neurotoxicity) following CAR-T-treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Thomas Pabst, Prof.  ·  +41 31 632 84 30  ·  thomas.pabst@insel.ch

Always discuss trial participation with your own doctor first.

Locations (1)

Insel Gruppe AGBern, Canton of Bern, SwitzerlandRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT06430736