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Study identifier: NCT06429280 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Clinical Data Registry of Amblyopia Patients on Luminopia Treatment

Condition: Amblyopia  ·  Sponsor: Luminopia

PhaseN/A
Planned participants500
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

Amblyopia is the most prevalent cause of reduced monocular visual acuity in children and young adults, with estimates of prevalence ranging from 1% to 5%. The most common associated amblyogenic risk factors are uncorrected anisometropia, strabismus, or a combination of these. In addition to reduced visual acuity, amblyopic patients may also have measurable dysfunction of accommodation, fixation, binocularity, vergence, reading fluency, depth perception, and contrast sensitivity. For the first time since the incorporation of atropine penalization into amblyopia management, physicians can now offer Luminopia, an FDA-approved dual action dichoptic treatment, to patients with amblyopia. Since the product became commercially available in November 2022, the number of patients on Luminopia therapy continues to grow. This presents a unique opportunity to gather real world evidence from a large number of patients, representative of how ophthalmologists and optometrists are applying this novel treatment in the real world. A registry of the clinical data associated with Luminopia treatment, with IRB oversight, will provide answers to key scientific questions using a large dataset.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (13)

UCSF Benioff Children's PhysiciansSan Ramon, California, United StatesRecruiting
Sansum ClinicSanta Barbara, California, United StatesRecruiting
Okaloosa OphthalmologyCrestview, Florida, United StatesRecruiting
Family Focus Eye CareGainsville, Florida, United StatesRecruiting
Eye Physicians of Central FloridaMaitland, Florida, United StatesRecruiting
Children's Eye Institute of SavannahSavannah, Georgia, United StatesRecruiting
Honolulu Eye ClinicHonolulu, Hawaii, United StatesRecruiting
Lurie Children's HospitalChicago, Illinois, United StatesRecruiting
Riley Children's Hospital at IU HealthIndianapolis, Indiana, United StatesRecruiting
Nevada Eye PhysiciansLas Vegas, Nevada, United StatesRecruiting
Concord Eye CenterConcord, New Hampshire, United StatesRecruiting
Children's Hospital Of PhiladelphiaPhiladelphia, Pennsylvania, United StatesRecruiting

+ 1 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06429280