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Study identifier: NCT06428188 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Sequential CAR-T Cells Targeting BCMA/CD19 in Patients With Relapsed/ Refractory Autoimmune Diseases

Condition: Autoimmune Diseases · Systemic Lupus Erythematosus · Systemic Lupus Erythematosus Acute  ·  Sponsor: Essen Biotech

PhasePhase 1/Phase 2
Planned participants60
Who can joinAll sexes, 21 Years to 90 Years
Healthy volunteersNo

About this study

This is an open, single-arm, clinical study to evaluate the efficacy and safety of chimeric antigen receptor T cell immunotherapy (CAR-T) targeting BCMA or CD19 or both sequentially in the treatment of Relapsed/ Refractory Autoimmune Disease such as Sjogren's Syndrome or Systemic Lupus Erythematosus and other Autoimmune Disease.

This description comes directly from the study's public registry record.

Talk to the study team

Rhoda M Smith, Phd  ·  +12077706670  ·  clinical-trials@essen-biotech.com

Always discuss trial participation with your own doctor first.

Locations (1)

District One HospitalBeijing, Beijing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06428188