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Study identifier: NCT06425978 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Efficacy of the Use of Cellular Matrix/ A-CP-HA Kit

Condition: Genitourinary Syndrome of Menopause  ·  Sponsor: Fundación Santiago Dexeus Font

PhasePhase 4
Planned participants192
Who can joinFemale, 18 Years to 70 Years
Healthy volunteersNo

About this study

This study is a randomized, controlled, non-inferiority trial, that will be performed on 192 women on Menopause (absence of menstruation for at least 12 months), with diagnostic of genitourinary syndrome of menopause (SGM) and a vaginal health index \<15 points, that are sexually active. Patients will be randomized 1:1, equal number assigned to each of the two treatment groups, to receive treatment with two dose of Cellular Matrix / A-CP-HA Kit (a combination of autologous platelet-rich plasma and non-cross-linked hyaluronic acid) separated for a month, and control group that will receive the standard treatment for SGM, local estrogen therapy (Blissel, estriol 50 micrograms/g vaginal gel). Both groups will be follow-up for 3 and 6 month afther treatment, a blind observer will assess the application of the validated scale (VHIS, VHI), and the investigators will do the FSD, symptom record, maturation index, follow-up photography and evaluation of adverse events and treatment compliance and adherence.

This description comes directly from the study's public registry record.

Talk to the study team

Antonella de Ponte Davi, MD  ·  0034932274700  ·  ANTPON@dexeus.com

Ignacio Rodríguez, MSc  ·  0034932274700  ·  nacrod@dexeus.com

Always discuss trial participation with your own doctor first.

Locations (1)

Departamento de Ginecología Obstetricia y Reproducción. Hospital Universitari DexeusBarcelona, SpainRecruiting

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Source record: clinicaltrials.gov/study/NCT06425978