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Study identifier: NCT06425133 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Regorafenib in Combination With Multimodal Metronomic Chemotherapy for Chemo-resistant Metastatic Colorectal Cancers

Condition: Metastatic Colorectal Cancer  ·  Sponsor: Centre Hospitalier Universitaire de Besancon

PhasePhase 2
Planned participants174
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The main objective is to evaluate the impact of a Regorafenib combined with metronomic chemotherapy (capecitabine and cyclophosphamide) and low-dose aspirin compared to standard Regorafenib treatment in patients with metastatic colorectal cancer by assessing progression-free survival.

This description comes directly from the study's public registry record.

Talk to the study team

Angélique VIENOT, Dr  ·  +33 370632278  ·  a3vienot@chu-besancon.fr

Christophe BORG, Pr  ·  xtoph.borg@gmail.com

Always discuss trial participation with your own doctor first.

Locations (10)

CHU d'AuxerreAuxerre, FranceRecruiting
Centre Hospitalier Universitaire de BesançonBesançon, FranceRecruiting
CH de ColmarColmar, FranceRecruiting
Centre Georges-François Leclerc (CGFL)Dijon, FranceRecruiting
Hôpital Robert SchumanMetz, FranceRecruiting
Hôpital Nord Franche-ComtéMontbéliard, FranceRecruiting
CHU de MontpellierMontpellier, FranceRecruiting
CHU de Reims - Hôpital Robert DebréReims, FranceRecruiting
Clinique Privée de StrasbourgStrasbourg, FranceNot Yet Recruiting
ICANSStrasbourg, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT06425133