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Study identifier: NCT06424314 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Exploration of Mechanisms for Weaning Failure

Condition: Weaning Failure · Central Respiratory Depression · Diaphragm Injury  ·  Sponsor: The First Affiliated Hospital of Guangzhou Medical University

PhaseN/A
Planned participants30
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

This study is a prospective physiologic study. The primary study population will be adult invasive tracheal intubated patients with COPD, and investigators will collect relevant demographic data, vital signs, and baseline physiologic parameters of the patients prior to the spontaneous breathing test(SBT). The participants will be divided into a successful withdrawal group and a failed withdrawal group according to the SBT outcome, and the changes in the above parameters during SBT will be compared between the two groups .

This description comes directly from the study's public registry record.

Talk to the study team

Lili Guan, MD & PhD  ·  020-81566675  ·  dr_nickguan@163.com

Qiaoyun Huang  ·  020-81566675  ·  huangqiaoyun23@foxmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

The First Hospital of Guangzhou Medical UniversityGuangzhou, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06424314