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Study identifier: NCT06423573 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study to Assess the Incidence of Skin Cancers in Patients With Epidermolysis Bullosa Receiving Filsuvez

Condition: Epidermolysis Bullosa, Dystrophic · Epidermolysis Bullosa, Junctional  ·  Sponsor: Amryt Pharma

PhaseN/A
Planned participants580
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

In patients with epidermolysis bullosa (EB), collagen does not form properly, so their skin is very fragile and blisters easily. Such patients are also at greatly increased risk of developing skin cancers. Filsuvez is a topical gel used to promote healing of skin lesions in patients with certain types of EB. In this observational study, patients with either dystrophic EB (DEB) or junctional EB (JEB) will receive standard of care treatment, whether Filsuvez or something else, and will be followed for up to 5 years. The main purpose is to see if the use of Filsuvez affects the likelihood of developing skin malignancies in these patient populations.

This description comes directly from the study's public registry record.

Talk to the study team

Chiesi Clinical Trials  ·  +3905212791  ·  clinicaltrials_info@chiesi.com

Always discuss trial participation with your own doctor first.

Locations (5)

CHU de Toulouse, Hôpital LarreyToulouse, FranceRecruiting
Hospital of Skin and Venereal Diseases of ThessalonikiThessaloniki, GreeceRecruiting
Hospital Clinic, BarcelonaBarcelona, SpainRecruiting
Hospital San Juan de Dios (Barcelona)Barcelona, SpainRecruiting
Guy's and St Thomas' NHS Foundation TrustLondon, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT06423573