Condition: Diaphragm Dysfunction · Sponsor: Assistance Publique - Hôpitaux de Paris
ICU survivors are at an increased risk of hospital and ICU readmission. Among the complications of ICU stay, diaphragmatic dysfunction is common, with a prevalence of 60 to 80%, and is associated with increased mortality and prolonged hospital stays. Furthermore, several studies have reported that the observation of impaired respiratory muscle function upon ICU discharge is associated with a poor long-term prognosis. However, the incidence and prognostic impact of persistent diaphragmatic dysfunction at ICU discharge have never been evaluated. The measurement of dyspnea, a composite evaluation of respiratory muscle function, has not been assessed for predicting prognosis upon ICU discharge. The hypothesis of the project is that the presence of ICU-acquired diaphragmatic dysfunction at ICU discharge is associated with a poorer prognosis within 90 days.
This description comes directly from the study's public registry record.
Martin Dres, MD,PHD · 0142167809 · martin.dres@aphp.fr
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| Médecine intensive Réanimation | Paris, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06420999