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Study identifier: NCT06420167 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

DapagliFLOzin in Renal AL Amyloidosis (FLORAL)

Condition: Renal AL Amyloidosis  ·  Sponsor: Barbara Ann Karmanos Cancer Institute

PhasePhase 2
Planned participants20
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if an oral drug called dapagliflozin is safe and can reduce high protein levels in the urine of patients with renal amyloid light-chain (AL) amyloidosis using a decentralized study design. Participants will be: * screened for the trial via an online platform * contacted by study personal to obtain electronic consent * enrolled in the trial if eligible and consented * contacted by study personal for further instructions and directions * sent dapagliflozin oral medication (supplied by the site pharmacy) * followed up regularly with the study team via telemedicine or other online avenues * monitored using lab work, inquiries about side effects and assessment of protocol adherence at 1 month, 3 months and 6 months * continue treatment for 6 months

This description comes directly from the study's public registry record.

Talk to the study team

Christiane Houde  ·  3135768673  ·  Houdec@karmanos.org

Jeffrey Zonder, M.D.  ·  3135768732  ·  zonderj@karmanos.org

Always discuss trial participation with your own doctor first.

Locations (1)

Karmanos Cancer InstituteDetroit, Michigan, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06420167