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Study identifier: NCT06417801 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Minimally Interventional Study on Prevalence of Emerging ESR1 Mutations in Liquid Biopsy in Three Cohorts of Patients With Breast Cancer in Comparison With Patient's Baseline ESR1 Mutation Status as Defined by Tissue Profiling.

Condition: Metastatic Breast Cancer  ·  Sponsor: AstraZeneca

PhaseN/A
Planned participants170
Who can joinAll sexes, 18 Years to 100 Years
Healthy volunteersNo

About this study

Minimally interventional study on prevalence of emerging ESR1 mutations in liquid biopsy in three cohorts of patients with breast cancer (with and without prior therapies in metastatic setting, and during first-line aromatase inhibitor plus CDK4/6 inhibitor therapy) in comparison with patient's baseline ESR1 mutation status as defined by tissue profiling.

This description comes directly from the study's public registry record.

Talk to the study team

AstraZeneca Clinical Study Information Center  ·  1-877-240-9479  ·  information.center@astrazeneca.com

Always discuss trial participation with your own doctor first.

Locations (6)

Ensino E Terapia de Inovação Clínica Amo - ÉticaSalvador, Estado de Bahia, BrazilNot Yet Recruiting
Irmandade Da Santa Casa de Misericórdia de Porto AlegrePorto Alegre, Rio Grande do Sul, BrazilNot Yet Recruiting
Fundação Antonio Prudente - A.C. Camargo Cancer CenterSão Paulo, BrazilNot Yet Recruiting
Instituto D'Or de Pesquisa E Ensino - São PauloSão Paulo, BrazilNot Yet Recruiting
Research SiteSão Paulo, BrazilRecruiting
Sociedade Beneficente Israelita Brasileira Hospital Albert EisnteinSão Paulo, BrazilNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06417801