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Study identifier: NCT06416410 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

JAB-21822 Combined With JAB-3312 Compared SOC in the First Line for Treatment of Advanced Non-small Cell Lung Cancer With KRAS p.G12C Mutation

Condition: Advanced Non-squamous Non-small-cell Lung Cancer · Metastatic Non-squamous Non Small Cell Lung Cancer  ·  Sponsor: Allist Pharmaceuticals, Inc.

PhasePhase 3
Planned participants392
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This Phase 3 study will evaluate the efficacy of JAB-21822+JAB-3312 versus tislelizumab (PD-1 Ab) combined with pemetrexed+carboplatin as the first line treatment in subjects with KRAS G12C mutated locally advanced or metastatic non-small cell lung cancer (NSCLC).

This description comes directly from the study's public registry record.

Talk to the study team

Shanghai Allist Pharmaceuticals Co., Ltd  ·  021-80423288  ·  zhenhua.gong@allist.com.cn

Always discuss trial participation with your own doctor first.

Locations (37)

Anhui Province cancer hospitalHefei, Anhui, ChinaNot Yet Recruiting
Pecking Union Medical College HospitalBeijing, Beijing Municipality, ChinaNot Yet Recruiting
Cancer Hospital Chinese Academy Of Medical SciencesBeijing, Beijing Municipality, ChinaRecruiting
Beijing Tiantan Hospital, Captal Medical UniversityBeijing, Beijing Municipality, ChinaNot Yet Recruiting
Beijing Cancer HospitalBeijing, Beijing Municipality, ChinaRecruiting
Peking University Third HospitalBeijing, Beijing Municipality, ChinaRecruiting
Beijing Chest Hospital ,Capital Medical UniversityBeijing, Beijing Municipality, ChinaRecruiting
Fujian cancer HospitalFuzhou, Fujian, ChinaNot Yet Recruiting
The first Affiliated Hospital, Sun Yat-sen UniversityGuangzhou, Guangdong, ChinaNot Yet Recruiting
Cancer Hospital Chinese Academy Of medical Sciences Shenzhen CenterShenzhen, Guangdong, ChinaNot Yet Recruiting
Guangxi Medical University Cancer hospital & Guangxi Cancer InstituteNanning, Guangxi, ChinaNot Yet Recruiting
Cangzhou hospital of integrated TCM-WM HebeiCangzhou, Hebei, ChinaRecruiting

+ 25 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06416410