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Study identifier: NCT06415955 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Identification of Limiting Factors in the Locomotor Activity of Individuals With Lower Limb Amputation:

Condition: Lower Limb Amputation  ·  Sponsor: Centre Hospitalier Universitaire de Nīmes

PhaseN/A
Planned participants200
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

The experience of amputation leads to a deterioration in quality of life, with undeniable somatic and functional repercussions. The result is a reduction in general mobility, increased metabolic energy requirements and a feeling of discomfort and pain. The rehabilitation objectives focus on improving, or at least maintaining, the range of movement of the lower limbs, strengthening the overall muscles, ensuring that the equipment is correctly adapted, re-training for physical exertion and working on balance and walking. The rehabilitation objectives focus on social inclusion with the equipment, to optimise the return home and promote social and professional reintegration, and therapeutic education. Factors influencing the postoperative resumption of walking in amputees have been identified as key elements in the success of rehabilitation management. These include maintaining joint range of motion before fitting any equipment, combating postoperative loss of muscle mass, managing cardiorespiratory deconditioning and, finally, resuming walking with the aid of equipment, taking account of fluctuating balance. The literature shows that a change in the centre of gravity and postural instability, particularly when changing stance, are responsible for a greater risk of falls in lower-limb amputees. This asymmetry of gait, which is the cause of a greater risk of secondary joint degeneration, is found in both transtibial and transfemoral amputees. This alteration in balance has a dire…

This description comes directly from the study's public registry record.

Talk to the study team

Eric PANTERA  ·  +(33)4.66.68.25.36  ·  eric.pantera@chu-nimes.fr

Always discuss trial participation with your own doctor first.

Locations (1)

CHU de NîmesNîmes, Gard, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT06415955