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Study identifier: NCT06414759 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Efficacy and Safety of Combination Diuretic Therapy in Patients With Acute Decompensated Heart Failure and Volume Overload

Condition: Acute Decompensated Heart Failure · Volume Overload · Edema  ·  Sponsor: Cairo University

PhasePhase 4
Planned participants110
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

This study aims to compare two medications, acetazolamide and metolazone, along with loop diuretics, to see which one works better and is safer for patients with ADHF who have volume overload. By comparing these medications, we hope to learn which one can help these patients the most. This will help doctors choose the best treatment for patients with ADHF and volume overload.

This description comes directly from the study's public registry record.

Talk to the study team

Mohamed AN Abdelmoaty, B.Sc. Pharmaceutical Sciences  ·  +201146631157  ·  mohamed.naguib@miuegypt.edu.eg

Always discuss trial participation with your own doctor first.

Locations (1)

National Heart InstituteGiza, GZ, EgyptRecruiting

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Source record: clinicaltrials.gov/study/NCT06414759