← Eichor
Study identifier: NCT06414460 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study of ISM3412 in Participants With Locally Advanced/Metastatic Solid Tumors

Condition: Locally Advanced/Metastatic Solid Tumors  ·  Sponsor: InSilico Medicine Hong Kong Limited

PhasePhase 1/Phase 2
Planned participants114
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The study has consists of two parts, a dose escalation part (Part 1) and a dose selection optimization part (Part 2). The primary objectives of this study are to evaluate the safety and tolerability of ISM3412 in participants with locally advanced/metastatic solid tumors, and to determine the RP2D of ISM3412.

This description comes directly from the study's public registry record.

Talk to the study team

Johnny Ju  ·  +86 021-50831718  ·  Insilico-Clinicaltrial@insilico.ai

Always discuss trial participation with your own doctor first.

Locations (10)

Sarah Cannon Research Institute at HealthONEDenver, Colorado, United StatesRecruiting
Smilow Cancer Hospital at Yale New Haven Breast CenterNew Haven, Connecticut, United StatesRecruiting
Community Cancer Center NorthIndianapolis, Indiana, United StatesRecruiting
SCRI Oncology PartnersNashville, Tennessee, United StatesRecruiting
The University of Texas MD Anderson Cancer CenterHouston, Texas, United StatesRecruiting
Cancer Hospital Chinese Academy of Medical SciencesBeijing, Beijing Municipality, ChinaRecruiting
Peking University People's HospitalBeijing, Beijing Municipality, ChinaRecruiting
Sun Yat-sen university cancer centerGuangzhou, Guangdong, ChinaRecruiting
Jiangsu Provincial People's HospitalNanjing, Jiangsu, ChinaRecruiting
Shanghai Gobroad Cancer HospitalShanghai, Shanghai Municipality, ChinaRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT06414460