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Study identifier: NCT06413979 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Family Support Protocol for Adolescent Internalizing Disorders

Condition: Internalizing Disorders · Substance Use Disorders  ·  Sponsor: The National Center on Addiction and Substance Abuse at Columbia University

PhaseNA
Planned participants60
Who can joinAll sexes, 13 Years to 21 Years
Healthy volunteersNo

About this study

This R34 will develop and test an adjunctive treatment protocol for addressing co-occurring internalizing disorders among adolescents enrolled in usual care for substance use problems. Internalizing disorders (ID), primarily depression and anxiety, are highly prevalent among youth receiving community-based treatment for substance use disorder (SUD). Comorbidity rates range from 30-70% due to the multiple developmental pathways by which adolescent SUD and ID cause and exacerbate one another. Moreover, unresolved ID issues significantly interfere with youth SUD treatment and recovery processes. Yet, the youth SUD clinical workforce is not systematically educated or trained in evidence-based practices for ID; thus, line services for youth SUD do not systematically target ID. The research literature offers a few integrated behavioral models for simultaneously treating both SUD and ID in youth; however, such models feature intensive manualized procedures that have proven cumbersome to scale and deliver in frontline settings. As a result, the clinical workforce, though desiring ID-focused training, currently has inadequate resources for treating ID effectively. A promising solution to diminish this quality gap is developing an adjunctive, modular protocol to augment routine care for comorbid SUD/ID by directly targeting ID as a key treatment goal: Family Support Protocol for Adolescent Internalizing Disorders (Fam-AID). As an adjunctive protocol, Fam-AID will not require clinician…

This description comes directly from the study's public registry record.

Talk to the study team

Nicole P Porter, PhD  ·  (212) 841-5211  ·  nporter@toendaddiction.org

Aaron Hogue, PhD  ·  212 841-5200  ·  ahogue@toendaddiction.org

Always discuss trial participation with your own doctor first.

Locations (4)

Gateway Community ServicesJacksonville, Florida, United StatesRecruiting
Lurie Children's HospitalChicago, Illinois, United StatesRecruiting
Indiana University School of MedicineIndianapolis, Indiana, United StatesRecruiting
Roberto Clemente CenterNew York, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06413979