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Study identifier: NCT06412120 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study Evaluating Safety, Tolerability, and Metabolism of Niraparib

Condition: Ovarian Cancer  ·  Sponsor: University of Miami

PhasePhase 4
Planned participants70
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to identify the genetic characteristic(s), specifically degree of African ancestry, and environmental characteristic(s) that appear to be related to the effects, both good and bad, that the maintenance treatment has women with ovarian cancer. In this study, an investigational medication called niraparib is being tested for the treatment of ovarian cancer. Niraparib works by blocking the ability of cancer cells to fix their genes. Cancer cells with damaged genes have a harder time growing and spreading in the body and can even die.

This description comes directly from the study's public registry record.

Talk to the study team

Matthew Schlumbrecht, MD, MPH  ·  305-243-2233  ·  mschlumbrecht@med.miami.edu

Always discuss trial participation with your own doctor first.

Locations (4)

Broward HealthFort Lauderdale, Florida, United StatesRecruiting
University of Florida JacksonvilleJacksonville, Florida, United StatesRecruiting
University of MiamiMiami, Florida, United StatesRecruiting
Ahmadu Bello University Teaching Hospital (ABUTH)Zaria, Kaduna State, NigeriaRecruiting

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Source record: clinicaltrials.gov/study/NCT06412120