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Study identifier: NCT06411431 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Early Chest Tube Removal After Surgery for Primary Spontaneous Pneumothorax: A Randomized Controlled Trial

Condition: Primary Spontaneous Pneumothorax  ·  Sponsor: Swedish Medical Center

PhaseNA
Planned participants200
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Video-assisted thoracoscopic surgery (VATS) with blebectomy/wedge resection plus pleurodesis is the standard of care for recurrent primary spontaneous pneumothorax (PSP) or, in certain instances, after the first episode. The chest tube from surgery is typically kept to suction until post-operative day (POD) 2 to allow for scarring of the lung to the chest to prevent recurrence. However, the scarring process takes place over a period of weeks and is there no data to support POD#2 as the best time to remove the chest tube. Also, shorter chest tube duration can lower length of stay, patient discomfort, and hospital cost. The goal of this randomized study is to determine if early removal (POD#1) of chest tube after video-assisted thoracoscopic surgery (VATS) with blebectomy/wedge resection plus chemical pleurodesis for primary spontaneous pneumothorax (PSP): * has no worse 2-year recurrence rate compared to standard removal (POD#2) * will lower length of stay compared to standard removal * will result in less complications or re-interventions compared to standard removal Participants will be asked to join prior to surgery. Following standard-of-care surgery, participants will be screened for randomization. If still eligible, participants will be randomized for early chest tube removal or standard removal. Early Removal will happen within 24 hours after surgery, with Standard Removal happening day 2 after surgery. Participants will follow-up with the study team for 2 years on …

This description comes directly from the study's public registry record.

Talk to the study team

Brian Louie, M.D.  ·  206-215-6800  ·  brian.louie@swedish.org

John Campbell, M.D.  ·  206-215-6800  ·  john.campbell@swedish.org

Always discuss trial participation with your own doctor first.

Locations (1)

Swedish Cancer InstituteSeattle, Washington, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06411431