Condition: Dystonic Tremor Syndrome · Sponsor: Radboud University Medical Center
Tremor occurs in up to 55% of dystonia patients, which is known as dystonic tremor syndrome (DTS). Tremor can be present in the body part affected by dystonia (dystonic tremor, DT), or an unaffected body part (tremor associated with dystonia, TAWD). DTS can be treated with botulinum neurotoxin (BoNT) injections, but BoNT is effective in only about 60-70% of patients. It is unknown which patients benefit most from BoNT treatment. The investigators aim to explore the associations between clinical and pathophysiological tremor characteristics and BoNT efficacy. To do so, the investigatorswill measure clinical, electrophysiological, ultrasonographic and (functional) magnetic resonance imaging ((f)MRI) characteristics before the start of BoNT treatment and measure BoNT efficacy after three three-monthly BoNT sessions.
This description comes directly from the study's public registry record.
Iris Visser, MSc · +310243616600 · iris.visser@radboudumc.nl
Rick Helmich, PhD · rick.helmich@radboudumc.nl
Always discuss trial participation with your own doctor first.
| Donders Centre for Cognitive Neuroimaging | Nijmegen, Gelderland, Netherlands | Recruiting |
| Radboud University Medical Center | Nijmegen, Gelderland, Netherlands | Recruiting |
| Canisius-Wilhelmina Ziekenhuis | Nijmegen, Gelderland, Netherlands | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06411028