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Study identifier: NCT06410833 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Belimumab After Rituximab in Resistant Primary Juvenile SS

Condition: Sjogren's Syndrome · Pediatric ALL  ·  Sponsor: Peking Union Medical College Hospital

PhasePhase 4
Planned participants15
Who can joinAll sexes, 5 Years to 18 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to explore the effectiveness of sequential use of rituximab and belimumab in the treatment of resistant primary juvenile Sjogren's syndrome. Does sequential use of rituximab and belimumab reduce the activity of SS in resistant patients Researchers will compare the disease activity before and after the treatment of sequential use of rituximab and belimumab to see if the therapy works to treat SS. Participants will: Recieve Rituximab each week for 2-4 times until B%\<0.5% or B#\<20×10\^6/L Recieve Belimumab 4 weeks after the last use of Rituximab, and then every 4 weeks until week 28

This description comes directly from the study's public registry record.

Talk to the study team

Zhou  ·  +86 01069156251  ·  yzhou11@tsinghua.org.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Peking Union Medical College HospitalBeijing, Beijing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06410833