Condition: SDH-Related Familial Paraganglioma · SDHx-Related Syndromes · SDH Gene Mutation · Sponsor: Assistance Publique - Hôpitaux de Paris
The primary objective of the PGL.EXPO-2 study is to test the hypothesis that exposure (occupational, environmental and/or domestic) to succinate dehydrogenase inhibitors (SDHi) could contribute to tumor emergence in subjects carrying a germline mutation in one of the SDHx genes.The primary endpoint will be the proportion of subjects (cases or controls) exposed to SDHi and the association with paraganglioma risk. In addition, a blood sample (10 ml on EDTA) will be proposed to the participants to the study
This description comes directly from the study's public registry record.
Alexandre Buffet, MD, PhD · 33-1-56093879 · alexandre.buffet@aphp.fr
Anne-Paule Gimenez-Roqueplo, MD, PhD · 33-1-56093881 · anne-paule.gimenez-roqueplo@aphp.fr
Always discuss trial participation with your own doctor first.
| CHU d'Angers | Angers, France | Active Not Recruiting |
| CHU Jean Minjoz Besançon | Besançon, France | Active Not Recruiting |
| Hôpital Louis Pradel | Bron, France | Active Not Recruiting |
| CHU de Caen | Caen, France | Active Not Recruiting |
| Hôpital Michalon - CHU Grenoble | Grenoble, France | Active Not Recruiting |
| CHU de Lille - Hôpital HURIEZ | Lille, France | Active Not Recruiting |
| Hopital de la Conception - Marseille | Marseille, France | Active Not Recruiting |
| CHU de Montpellier - Hôpital Lapeyronie | Montpellier, France | Active Not Recruiting |
| CHU de Nantes | Nantes, France | Active Not Recruiting |
| CHU de Nice -Hôpital Archet 2 | Nice, France | Active Not Recruiting |
| Hôpital Pitié-Salpêtrière - APHP | Paris, France | Active Not Recruiting |
| Hôpital Cochin - APHP | Paris, France | Active Not Recruiting |
+ 8 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06408402