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Study identifier: NCT06405607 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Psilocybin or Ketamine for Alcohol Use Disorder: An Active Comparator Trial

Condition: Alcohol Use Disorder · Alcohol Dependence · Alcohol Abuse  ·  Sponsor: University of Iowa

PhasePhase 2
Planned participants80
Who can joinAll sexes, 21 Years to 65 Years
Healthy volunteersNo

About this study

This study will collect data that measures the effects of a psychedelic intervention on patients struggling with alcohol use disorder (AUD). The study design will be a double blind, randomized, active-comparator trial with two study arms. Subjects randomized to Arm 1 (n=40) will receive individual psychotherapy sessions plus a 30 mg dose of psilocybin. Arm 2 subjects (n=40) will receive individual psychotherapy sessions and a 0.75 mg/kg dose of ketamine.

This description comes directly from the study's public registry record.

Talk to the study team

Lindsay E Golden, BS  ·  319-384-5243  ·  lindsay-golden@uiowa.edu

Peggy C Nopoulos, MD  ·  319-356-1144  ·  peggy-nopoulos@uiowa.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Iowa Health CareIowa City, Iowa, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06405607