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Study identifier: NCT06403878 Synced from ClinicalTrials.gov · July 29, 2026
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Safety and Efficacy of Neoadjuvant Immunochemotherapy in Elderly Patients With Resectable Esophageal Cancer

Condition: Esophageal Cancer  ·  Sponsor: Sichuan University

PhasePhase 2
Planned participants68
Who can joinAll sexes, 70 Years to 100 Years
Healthy volunteersNo

About this study

We intend to conduct a prospective single-arm clinical study to explore the efficacy and safety of immunochemotherapy in neoadjuvant therapy in elderly patients with advanced esophageal squamous cell carcinoma. Most previous randomized controlled studies (such as the 5010 study) have excluded older patients ≥70 years of age. However, in the real world, elderly patients with esophageal cancer account for a large number of patients, and elderly people have many complications and poor tolerance to treatment, which limits the application of synchronous chemoradiotherapy in this group. There is no standard treatment plan for patients over 70 years old, and the purpose of this study is to explore the effectiveness and safety of neoadjuvant immunochemotherapy in the treatment of this group of elderly people.

This description comes directly from the study's public registry record.

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Locations (1)

West-China HospitalChengdu, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06403878