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Study identifier: NCT06401421 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)

Condition: Breast Cancer  ·  Sponsor: Exact Sciences Corporation

PhaseN/A
Planned participants1800
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The EXActDNA-003 study will prospectively enroll participants who are planning to undergo chemotherapy for high-risk, early breast cancer, who are willing to provide tissue and blood specimens for circulating tumor DNA (ctDNA) analysis. Participants will be followed for up to 5.5 years.

This description comes directly from the study's public registry record.

Talk to the study team

NSABP Department of Site and Study Management Department of Site and Study Management  ·  1-800-270-3165  ·  industry.trials@nsabp.org

Always discuss trial participation with your own doctor first.

Locations (58)

Katmai Oncology Group - AnchorageAnchorage, Alaska, United StatesRecruiting
Stanford Cancer InstitutePalo Alto, California, United StatesRecruiting
Harbor-UCLA Medical Center - Hematology / OncologyTorrance, California, United StatesRecruiting
Kaiser Permanente Medical CenterVallejo, California, United StatesRecruiting
UCHealth Cancer Care - Anschutz Medical Campus - University of Colorado Cancer CenterAurora, Colorado, United StatesRecruiting
AdventHealth East Altamonte Oncology and HematologyAltamonte Springs, Florida, United StatesRecruiting
Mount Sinai Medical - Comprehensive Cancer CenterMiami Beach, Florida, United StatesRecruiting
Baptist Cancer Care - PlantationPlantation, Florida, United StatesRecruiting
St. Joseph's Women's HospitalTampa, Florida, United StatesRecruiting
Rush Cancer CenterChicago, Illinois, United StatesRecruiting
Deaconess Chancellor Center for OncologyNewburgh, Indiana, United StatesRecruiting
University of Kansas Cancer CenterWestwood, Kansas, United StatesRecruiting

+ 46 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06401421