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Study identifier: NCT06401330 Synced from ClinicalTrials.gov · July 29, 2026
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A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

Condition: Stage I Mixed Cell Type Kidney Wilms Tumor · Stage II Mixed Cell Type Kidney Wilms Tumor · Stage III Mixed Cell Type Kidney Wilms Tumor  ·  Sponsor: Children's Oncology Group

PhasePhase 3
Planned participants1656
Who can joinAll sexes, N/A to 30 Years
Healthy volunteersNo

About this study

This phase III trial studies using risk factors in determining treatment for children with favorable tissue (histology) Wilms tumors (FHWT). Wilms Tumor is the most common type of kidney cancer in children, and FHWT is the most common subtype. Previous large clinical trials have established treatment plans that are likely to cure most children with FHWT, however some children still have their cancer come back (called relapse) and not all survive. Previous research has identified features of FHWT that are associated with higher or lower risks of relapse. The term "risk" refers to the chance of the cancer coming back after treatment. Using results of tumor histology tests, biology tests, and response to therapy may be able to improve treatment for children with FHWT.

This description comes directly from the study's public registry record.

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Contact details are listed per location below or on the registry record.

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Locations (159)

Children's Hospital of AlabamaBirmingham, Alabama, United StatesRecruiting
USA Health Strada Patient Care CenterMobile, Alabama, United StatesRecruiting
Providence Alaska Medical CenterAnchorage, Alaska, United StatesRecruiting
Banner Children's at DesertMesa, Arizona, United StatesRecruiting
Phoenix Childrens HospitalPhoenix, Arizona, United StatesRecruiting
Arkansas Children's HospitalLittle Rock, Arkansas, United StatesRecruiting
Kaiser Permanente Downey Medical CenterDowney, California, United StatesRecruiting
Loma Linda University Medical CenterLoma Linda, California, United StatesRecruiting
Miller Children's and Women's Hospital Long BeachLong Beach, California, United StatesRecruiting
Cedars-Sinai Medical CenterLos Angeles, California, United StatesRecruiting
Valley Children's HospitalMadera, California, United StatesRecruiting
UCSF Benioff Children's Hospital OaklandOakland, California, United StatesRecruiting

+ 147 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06401330