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Study identifier: NCT06399107 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Investigation Into the Use of BAH243 Lentiviral Vector for Gene Therapy in Treating Sickle Cell Disease

Condition: Sickle Cell Disease · Sickle-Cell Disease With Crisis  ·  Sponsor: Essen Biotech

PhasePhase 1/Phase 2
Planned participants85
Who can joinAll sexes, 2 Years to 90 Years
Healthy volunteersNo

About this study

This study is an open-label, non-randomized, single-dose Phase 1/2 trial involving around 85 adult and pediatric participants aged between 2 and 50 years with sickle cell disease (SCD). It aims to assess the effectiveness of hematopoietic stem cell transplantation (HSCT) using BAH243 for SCD.

This description comes directly from the study's public registry record.

Talk to the study team

Rhoda M Smith, Phd  ·  +12077706670  ·  clinical-trials@essen-biotech.com

Always discuss trial participation with your own doctor first.

Locations (1)

District One HospitalBeijing, Beijing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06399107