Condition: Neuromyelitis Optica · Sponsor: University of Texas Southwestern Medical Center
This is an observational study to: * evaluate the on-treatment clinical performance of ravulizumab in relation to the pre-treatment time period (time period prior to exposure), * enhance knowledge regarding conventional MRI outcomes in people with NMOSD treated with ravulizumab, * identify factors suggestive of subclinical disease progression through conventional MRI sequences, * determine if treatment with ravulizumab, impacts longitudinal 3D conformational MRI measures at the dorsal medulla and other regions of the CNS, and * identify biomarkers (e.g., serum neurofilament light chain (sNfL), conventional and novel MRI markers, etc.) related to disease activity.
This description comes directly from the study's public registry record.
Diem Tran, PhD · 214-645-9165 · diemh.tran@utsouthwestern.edu
Jose Santoyo · 214-645-1878 · jose.santoyo@utsouthwestern.edu
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| UT Southwestern Medical Center | Dallas, Texas, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06398158