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Study identifier: NCT06397313 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

RVU120 in Patients With Intermediate or High-risk, Primary or Secondary Myelofibrosis

Condition: Myelofibrosis  ·  Sponsor: Ryvu Therapeutics SA

PhasePhase 2
Planned participants230
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The objective of this clinical trial is to evaluate the efficacy (how well the drug works), safety, pharmacokinetics (PK), and pharmacodynamics (PD) of the study drug, RVU120, in treating adult patients with intermediate or high-risk, primary or secondary myelofibrosis. RVU120 will be given as a single agent or in combination with ruxolitinib.

This description comes directly from the study's public registry record.

Talk to the study team

Head of Clinical Operations  ·  48 123140200  ·  clinicaltrials@ryvu.com

Always discuss trial participation with your own doctor first.

Locations (18)

Policlinico Sant'Orsola-MalpighiBologna, ItalyRecruiting
Azienda Socio Sanitaria Territoriale Degli Spedali Civili Di BresciaBrescia, ItalyRecruiting
Azienda Ospedaliero Universitaria Policlinico "G. Rodolico - San Marco"Catania, ItalyRecruiting
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l.Meldola, ItalyRecruiting
Fondazione IRCCS Cà Granda Ospedale Maggiore PoliclinicoMilan, ItalyRecruiting
Wojewódzki Szpital Specjalistyczny w Białej PodlaskiejBiała Podlaska, PolandRecruiting
Szpital Uniwersytecki nr 2 im. dr Jana BizielaBydgoszcz, PolandRecruiting
M2M Med. Sp. z o.o. Sp. j.Chorzów, PolandRecruiting
Centrum Wsparcia Badań Klinicznych UCK Ośrodek Badań Klinicznych Wczesnych FazGdansk, PolandRecruiting
Pratia Hematologia Sp. z o.o.Katowice, PolandRecruiting
Świętokrzyskie Centrum Onkologii Samodzielny Publiczny Zakład Opieki ZdrowotnejKielce, PolandCompleted
Samodzielny Publiczny Zakład Opieki Zdrowotnej Szpital Uniwersytecki w KrakowieKrakow, PolandRecruiting

+ 6 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06397313