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Study identifier: NCT06394674 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

High-dose Furmonertinib in the Treatment in Patients With Advanced, Metastatic NSCLC With Progressed After First- or Second-line Treatment With Osimertinib

Condition: Non-Small Cell Lung Cancer  ·  Sponsor: Changhai Hospital

PhasePhase 2
Planned participants84
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This is a prospective, randomised, uncontrolled phase II clinical trial planned to include 84 subjects with metastatic lung adenocarcinoma that had progressed after first- or second-line treatment with Osmertinib, who were randomly assigned to trial group 1 and trial group 2, and were given Furmonertinib 160 mg and 240 mg once/day, orally, respectively, with efficacy evaluated every 6 weeks until disease progression, intolerable toxic side effects, or Subjects voluntarily withdrew informed consent.

This description comes directly from the study's public registry record.

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Locations (1)

Changhai HospitalShanghai, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06394674