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Study identifier: NCT06393816 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

FIRST-NEC (GFPC 01-2022) - Combination of Durvalumab With Etoposide and Platinum

Condition: Large Cell Neuroendocrine Carcinoma of the Lung  ·  Sponsor: Centre Leon Berard

PhasePhase 2
Planned participants80
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The primary objective is to determine the efficacy (Progression-Free Rate at 12 months) of durvalumab combined with etoposide and platinum (either cisplatin or carboplatin) for the first-line treatment of patients with advanced LCNEC confirmed by centralized expert-pathologist review

This description comes directly from the study's public registry record.

Talk to the study team

Julien GAUTIER  ·  +33 4 26 55 68 29  ·  julien.gautier@lyon.unicancer.fr

Luc ODIER, MD  ·  lodier@hno.fr

Always discuss trial participation with your own doctor first.

Locations (31)

Centre Hospitalier Intercommunal Aix-PertuisAix-en-Provence, FranceActive Not Recruiting
Chu Amiens Picardie Site SudAmiens, FranceNot Yet Recruiting
Chu AngersAngers, FranceNot Yet Recruiting
CENTRE HOSPITALIER d'AVIGNONAvignon, FranceNot Yet Recruiting
CHU BREST Cavale BlancheBrest, FranceNot Yet Recruiting
Centre Francois BaclesseCaen, FranceNot Yet Recruiting
Chu Gabriel MontpiedClermont-Ferrand, FranceNot Yet Recruiting
Centre Hospitalier Intercommunal de CreteilCréteil, FranceNot Yet Recruiting
Chu Annecy GenevoisÉpagny, FranceActive Not Recruiting
Chu Grenoble AlpesGrenoble, FranceRecruiting
Centre Oscar LambretLille, FranceNot Yet Recruiting
Chu DupuytrenLimoges, FranceRecruiting

+ 19 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06393816