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Study identifier: NCT06391892 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Liquid Biopsy (ctDNA) Guided Treatment in Localized Pancreatic Cancer: Neoadjuvant CTX vs. Upfront Surgery

Condition: Pancreatic Cancer · Circulating Tumor Cell · Predictive Cancer Model  ·  Sponsor: Elisabethinen Hospital

PhasePhase 3
Planned participants100
Who can joinAll sexes, 18 Years to 99 Years
Healthy volunteersNo

About this study

This study evaluates the clinical prognostic impact (on DFS and OS) of liquid biopsy guided treatment vs. standard of care (physicians choice) in localized pancreatic cancer (despite because of CA 19-9 levels and computed tomography, upfront surgery is recommended by tumor board). ctDNA positive patients will receive neoadjvuant chemotherapy at current gold standard physicians choice instead of upfront surgery, because of assumed high biological risk for early recurrence.

This description comes directly from the study's public registry record.

Talk to the study team

Patrick Kirchweger, MD, PhD  ·  +436644159646  ·  patrick.kirchweger@ordensklinikum.at

Helwig Wundsam, PD, MD  ·  +4373276774562  ·  helwig.wundsam@ordensklinikum.at

Always discuss trial participation with your own doctor first.

Locations (1)

Ordensklinikum Linz Barmherzige SchwesternLinz, Upper Austria, AustriaRecruiting

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Source record: clinicaltrials.gov/study/NCT06391892