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Study identifier: NCT06389994 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Esophageal String Test Monitoring to Monitor Eosinophilic Esophagitis During Oral Immunotherapy

Condition: Eosinophilic Esophagitis (EoE)  ·  Sponsor: Children's Hospital of Philadelphia

PhaseN/A
Planned participants75
Who can joinAll sexes, 7 Years to 17 Years
Healthy volunteersNo

About this study

Patients with IgE mediated food Allergy have elevated risk of eosinophilic esophagitis, and new therapies like oral immunotherapy (OIT) carry additional risk of Eosinophilic Esophagitis (EoE). The goal of this study is to investigate the Esophageal String Test (EST) as a screening tool for Eosinophilic Esophagitis (EoE) during OIT therapy. Investigators will compare the efficacy of the Esophageal String Test to symptom assessment using a validated patient reported symptom questionnaire, the Pediatric Eosinophilic Esophagitis Symptom Score (PEESS) v2.0. Investigators will utilize these tools to screen patients at their baseline visit prior to the start of OIT, then at the 3- and 6-month OIT follow-up visits.

This description comes directly from the study's public registry record.

Talk to the study team

Sharon A Carbonara, MS, BSN, RN  ·  267.426.8603  ·  carbonara@chop.edu

Always discuss trial participation with your own doctor first.

Locations (1)

The Children's Hospital of PhiladelphiaPhiladelphia, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06389994