Condition: B-cell Acute Lymphoblastic Leukemia · Acute Lymphoblastic Leukemia, in Relapse · Refractory Acute Lymphoid Leukemia · Sponsor: Beijing GoBroad Hospital
This is a single-center, double-blind, randomized trial. Patients with relapsed or refractory acute B-lymphoblastic leukemia(r/r B-ALL) experiencing early functional exhaustion of CAR-T cells will be randomly allocated into three groups: the control cell group, the CIK treatment group, and the messenger RNA(mRNA)-CIK treatment group. The primary objective of the study is to evaluate the prognostic impact of CIK cell therapy on the early functional exhaustion of CAR-T cells in children and adolescent and young adult (AYA) with r/r B-ALL. The primary endpoint of the study is the event-free survival rate of these patient in the CIK cell therapy group.A total number of 213 subjects will be enrolled.
This description comes directly from the study's public registry record.
Tengyu Wang · 86+18333186020 · tengyu.wang@gohealtharo.com
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| Beijing GoBroad Hospital | Beijing, Beijing Municipality, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06389305