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Study identifier: NCT06388031 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

ICI Rechallenge for Advanced NSCLC With Long-Term Response to First-Line ICI

Condition: Non-small Cell Lung Cancer  ·  Sponsor: Peking Union Medical College Hospital

PhasePhase 2
Planned participants27
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

An exploratory phase II trial of immune checkpoint inhibitors (ICIs, anti-PD-1/anti-PD-L1) as second-line treatment with advanced non-small cell lung cancer (NSCLC) who had long-term response to first-line immunotherapy (with or without chemotherapy). This study aims to evaluate efficacy and safety of ICI rechallenge in long-term responders to prior ICI. Furthermore, it seeks to identify biomarkers capable of predicting the efficacy of immunotherapy and prognosis.

This description comes directly from the study's public registry record.

Talk to the study team

Minjiang Chen, MD.  ·  +8618618340880  ·  minjiangchen@163.com

Mengzhao Wang, MD.  ·  +8613911235467  ·  mengzhaowang@sina.com

Always discuss trial participation with your own doctor first.

Locations (1)

Peking Union Medical College HospitalBeijing, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06388031