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Study identifier: NCT06386705 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

TSN084 Treating Patients With Advanced Malignant Tumors

Condition: Malignant Neoplasm  ·  Sponsor: Tyligand Bioscience (Shanghai) Limited

PhasePhase 1
Planned participants114
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

TSN084 is a novel type II kinase inhibitor with demonstrated anti-tumor effects in vitro and in vivo and targets multiple tyrosine kinases, such as c-MET, FLT3, TRK and serine/threonine kinase CDK8/19. This phase 1a/1b study is conducted to assess the maximum tolerated dose (MTD) and dose-limiting toxicity (DLT), to evaluate the pharmacokinetics, safety and preliminary anti-tumor activity of TSN084 in advanced or metastatic malignancies in China.

This description comes directly from the study's public registry record.

Talk to the study team

Tyligand Clinical Trial Info  ·  +86-021-50720081  ·  clinical_trial@tyligand.com

Always discuss trial participation with your own doctor first.

Locations (2)

Cancer Hospital Chinese Academy of Medical SciencesBeijing, Beijing Municipality, ChinaRecruiting
Peking university cancer hospitalBeijing, Beijing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06386705