Condition: Stroke · Sponsor: Université de Sherbrooke
Following a stroke, persistent residual muscle weakness in the upper limb (UL) drastically impacts the individuals' quality of life and level of independence. Training interventions are recommended to promote UL motor recovery, and recent studies have shown that training must be tailored to each individual's recovery potential to maximise training gains. Complementary to training interventions, non-invasive brain stimulation devices (NIBS) can help support the provision of post-stroke care by modulating brain excitability and enhancing recovery. Among NIBS, cranial nerve non-invasive neuromodulation (CN-NINM) is gaining increasing attention in rehabilitation since it can directly and non-invasively stimulate the tongue's cranial nerves. The impulses generated can then reach the motor cortex, induce neuroplastic changes and support recovery. Promising results in various neurological populations have been observed, but in stroke, the efficacy of CN-NINM at improving arm motor recovery and brain plasticity is yet to be determined. This is what the present project intends to address, using a stratified randomized controlled trial, where participants in the chronic phase of a stroke will take part in a 4-week individualized training program of their affected UL in combination with real or sham CN-NINM. Before and after the intervention, participants will undergo clinical and neurophysiological evaluations to thoroughly evaluate CN-NINM-induced changes in UL motor function and asso…
This description comes directly from the study's public registry record.
Marie-Helene Milot, PhD · 819-780-2220 · marie-helene.milot@usherbrooke.ca
Maureen Ahiatsi, MsC · 819-780-2220 · maureen.rudy.sandra.ahiatsi@usherbrooke.ca
Always discuss trial participation with your own doctor first.
| CRIR/Feil/Oberfeld Research Center; Centre intégré de santé et de services sociaux de Laval; Jewish Rehabilitation Hospital | Laval, Quebec, Canada | Recruiting |
| CIRRIS | Québec, Quebec, Canada | Recruiting |
| Centre de recherche sur le vieillissement | Sherbrooke, Quebec, Canada | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06386510