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Study identifier: NCT06382636 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Engaging Patients in Prenatal Genetic Testing Decisions as a Pathway to Improve Obstetric Outcomes

Condition: Prenatal Disorder  ·  Sponsor: The Cleveland Clinic

PhaseNA
Planned participants600
Who can joinFemale, 18 Years to 50 Years
Healthy volunteersNo

About this study

The goal of this study is to ensure that pregnant patients have the resources and support needed to access Prenatal Screening \& Diagnostic Testing (PS\&D) in an informed and evidence-based fashion by developing an innovative digital tool to support patients' decision-making and contributing fundamental knowledge to advance science in a way that promotes patients' access to new prenatal applications of genomic science and technology. Our central hypothesis is that, by focusing on patient engagement as a key driver to improve patient outcomes, the use of an evidence-based artificial-intelligence (AI) powered patient engagement tool will increase patients' ability to seek information and structure a decision-making process that, in turn, increases informed decisions about PS\&D and decreases decisional conflict associated with those decisions. Using data from NEST (Ensuring Patients Informed Access to NIPT \[non-invasive prenatal testing\]), the investigators designed the next iteration of NEST, a point-of care shared decision-making tool powered by artificial intelligence (AI) to provide a personalized and dynamic decision support tool: Obstetric Prenatal Genetic Testing Engagement Solution (OPUS). OPUS is an AI-enabled healthcare chatbot (a computer program capable of processing and simulating human conversation) that provides patients with personalized information and decision-making support at different stages of the PS\&D pathway. It functions using a series of questions …

This description comes directly from the study's public registry record.

Talk to the study team

Ruth Farrell, MD, MA  ·  216-445-7085  ·  farrelr@ccf.org

Christina Collart, MEd  ·  216-470-9796  ·  collarc@ccf.org

Always discuss trial participation with your own doctor first.

Locations (3)

Neighborhood Family PracticeCleveland, Ohio, United StatesNot Yet Recruiting
MetroHealth Medical CenterCleveland, Ohio, United StatesNot Yet Recruiting
Cleveland ClinicCleveland, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06382636