Condition: Ureteropelvic Junction Obstruction · Chronic Kidney Diseases · Sponsor: University of Campania Luigi Vanvitelli
The goal of this observational study is to learn about specific biomarkers of unilateral ureteropelvic junction obstruction (UPJO) in children undergoing surgical intervention for unilateral UPJO compared with controls. The main question it aims to answer are: * Are Urinary single-cell and extracellular vesicles (EVs) screening useful to stage the intrarenal injury and repair processes in UPJO babies? * Do babies with unilateral UPJO have a whole blood gene expression profiling (WBGEP) allowing an accurate unilateral UPJO diagnosis?
This description comes directly from the study's public registry record.
Pierluigi Marzuillo, MD PhD · 00390815665344 · pierluigi.marzuillo@unicampania.it
Always discuss trial participation with your own doctor first.
| Univeristà degli Studi della Campania Luigi Vanvitelli | Naples, Campania, Italy | Recruiting |
| Department of Clinical Sciences and Community Health, University of Milano | Milan, Italy | Active Not Recruiting |
| Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico | Milan, Italy | Recruiting |
| Obstetrics and Gynecology Unit, University of Modena and Reggio Emilia | Modena, Italy | Recruiting |
| AORN Santobono-Pausilipon | Naples, Italy | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06382233